testosterone sitting in your androgen receptor

[Glycomann]

This is your androgen receptor with testosterone ligand bound to it's receptor site.

Note: testosterone does not have to be from World Pharma.com or FDA approved. It can be from your balls or any UGL.

 

[LightBearer]

so the test is all the lil squiggly things right?

 

[Glycomann]

so the test is all the lil squiggly things right?

no it's the gray ringy thing that looks like this..

 

[independent]

no it's the gray ringy thing that looks like this..

The gray thingy doesnt look FDA approved.

 

[Digitalash]

how does it "fit" into the receptor? From that pic it looks like its just kinda floating there and its shape doesn't seem like it matches up with the receptor site. Maybe a dumb question but I kind of always pictured receptors like puzzle pieces that fit the molecule, how does it really work?

no it's the gray ringy thing that looks like this..

 

[Glycomann]

how does it "fit" into the receptor? From that pic it looks like its just kinda floating there and its shape doesn't seem like it matches up with the receptor site. Maybe a dumb question but I kind of always pictured receptors like puzzle pieces that fit the molecule, how does it really work?

If I represented the receptor as it's true space filled form with all its volume including all side chains you would not be able to see the steroid molecule in its receptor site. As it is represented the testosterone molecule is in it's correct position and orientation according to the X-ray crystalographic data that was used to create the image. Here is the space filled representation.

 

[Digitalash]

gotcha, so how does it get inside? Or am I missing something that makes this another stupid question lol

If I represented the receptor as it's true space filled form with all its volume including all side chains you would not be able to see the steroid molecule in its receptor site. As it is represented the testosterone molecule is in it's correct position and orientation according to the X-ray crystalographic data that was used to create the image. Here is the space filled representation.

 

[LightBearer]

COOL! i wants to be riddled with thoes!

no it's the gray ringy thing that looks like this..

 

[TGB1987]

This is great Glycomann. Really nice to see this blown up.

 

[Glycomann]

gotcha, so how does it get inside? Or am I missing something that makes this another stupid question lol

A syringe and a hammer.